| http://purl.uniprot.org/citations/22696596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22696596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22696596 | http://www.w3.org/2000/01/rdf-schema#comment | "Lung cancer has become the top killer among malignant tumors in China and is significantly associated with somatic genetic alterations. We performed exome sequencing of 14 non-small cell lung carcinomas (NSCLCs) with matched adjacent normal lung tissues extracted from Chinese patients. In addition to the lung cancer-related genes (TP53, EGFR, KRAS, PIK3CA, and ROS1), this study revealed "novel" genes not previously implicated in NSCLC. Especially, matrix-remodeling associated 5 was the second most frequently mutated gene in NSCLC (first is TP53). Subsequent Sanger sequencing of matrix-remodeling associated 5 in an additional sample set consisting of 52 paired tumor-normal DNA samples revealed that 15% of Chinese NSCLCs contained somatic mutations in matrix-remodeling associated 5. These findings, together with the results from pathway analysis, strongly indicate that altered extracellular matrix-remodeling may be involved in the etiology of NSCLC."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.org/dc/terms/identifier | "doi:10.1093/carcin/bgs210"xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.org/dc/terms/identifier | "doi:10.1093/carcin/bgs210"xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Cui P."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Cui P."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li K."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li K."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Jiang H."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Jiang H."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Liu P."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Liu P."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Ma D."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Ma D."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Ding F."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Ding F."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Xu Q."xsd:string |
| http://purl.uniprot.org/citations/22696596 | http://purl.uniprot.org/core/author | "Xu Q."xsd:string |