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http://purl.uniprot.org/citations/2270487http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2270487http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2270487http://www.w3.org/2000/01/rdf-schema#comment"T lymphocyte activation requires recognition by the T cell of peptide fragments of foreign antigen bound to a self major histocompatibility complex (MHC) molecule. Genetic evidence suggests that part of the class II region of the MHC influences the expression, in trans, of MHC class I antigens on the cell surface, by regulating the availability of peptides that bind to and stabilize the class I molecule. Two closely related genes in this region, HAM1 and HAM2, were cloned and had sequence similarities to a superfamily of genes involved in the ATP-dependent transport of a variety of substrates across cell membranes. Thus, these MHC-linked transport protein genes may be involved in transporting antigen, or peptide fragments thereof, from the cytoplasm into a membrane-bounded compartment containing newly synthesized MHC molecules."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.org/dc/terms/identifier"doi:10.1126/science.2270487"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.org/dc/terms/identifier"doi:10.1126/science.2270487"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Cho S."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Cho S."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Monaco J.J."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Monaco J.J."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Attaya M."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/author"Attaya M."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/pages"1723-1726"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/pages"1723-1726"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/title"Transport protein genes in the murine MHC: possible implications for antigen processing."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/title"Transport protein genes in the murine MHC: possible implications for antigen processing."xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/volume"250"xsd:string
http://purl.uniprot.org/citations/2270487http://purl.uniprot.org/core/volume"250"xsd:string
http://purl.uniprot.org/citations/2270487http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2270487
http://purl.uniprot.org/citations/2270487http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2270487
http://purl.uniprot.org/citations/2270487http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2270487
http://purl.uniprot.org/citations/2270487http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2270487