| http://purl.uniprot.org/citations/22720667 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22720667 | http://www.w3.org/2000/01/rdf-schema#comment | "We developed m:Explorer for identifying process-specific transcription factors (TFs) from multiple genome-wide sources, including transcriptome, DNA-binding and chromatin data. m:Explorer robustly outperforms similar techniques in finding cell cycle TFs in Saccharomyces cerevisiae. We predicted and experimentally tested regulators of quiescence (G0), a model of ageing, over a six-week time-course. We validated nine of top-12 predictions as novel G0 TFs, including Δmga2, Δcst6, Δbas1 with higher viability and G0-essential TFs Tup1, Swi3. Pathway analysis associates longevity to reduced growth, reprogrammed metabolism and cell wall remodeling. m:Explorer (http://biit.cs.ut.ee/mexplorer/) is instrumental in interrogating eukaryotic regulatory systems using heterogeneous data."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.org/dc/terms/identifier | "doi:10.1186/gb-2012-13-6-r55"xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Luscombe N.M."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Sedman J."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Vaquerizas J.M."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Reimand J."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Vilo J."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/author | "Aun A."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/name | "Genome Biol"xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/pages | "R55"xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/title | "m:Explorer: multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence."xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/22720667 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22720667 |
| http://purl.uniprot.org/citations/22720667 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22720667 |
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| http://purl.uniprot.org/uniprot/#_P40535-mappedCitation-22720667 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22720667 |
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