| http://purl.uniprot.org/citations/22728137 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22728137 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22728137 | http://www.w3.org/2000/01/rdf-schema#comment | "Gp78 is an E3 ubiquitin ligase within the endoplasmic reticulum-associated degradation pathway. We show that Flag-tagged gp78 undergoes sulfhydryl cysteine palmitoylation (S-palmitoylation) within the RING finger motif, responsible for its ubiquitin ligase activity. Screening of 19 palmitoyl acyl transferases (PATs) identified five that increased gp78 RING finger palmitoylation. Endoplasmic reticulum (ER)-localized Myc-DHHC6 overexpression promoted the peripheral ER distribution of Flag-gp78 while RING finger mutation and the palmitoylation inhibitor 2-bromopalmitate restricted gp78 to the central ER. Palmitoylation of RING finger cysteines therefore regulates gp78 distribution to the peripheral ER."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.06.011"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.06.011"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Huang K."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Huang K."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Nabi I.R."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Nabi I.R."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "El-Husseini A."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "El-Husseini A."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Fairbank M."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/author | "Fairbank M."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/pages | "2488-2493"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/pages | "2488-2493"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/title | "RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/title | "RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase."xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22728137 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22728137 |
| http://purl.uniprot.org/citations/22728137 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22728137 |