| http://purl.uniprot.org/citations/22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22730331 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein modification by SUMO and ubiquitin critically impacts genome stability via effectors that "read" their signals using SUMO interaction motifs or ubiquitin binding domains, respectively. A novel mixed SUMO and ubiquitin signal is generated by the SUMO-targeted ubiquitin ligase (STUbL), which ubiquitylates SUMO conjugates. Herein, we determine that the "ubiquitin-selective" segregase Cdc48-Ufd1-Npl4 also binds SUMO via a SUMO interaction motif in Ufd1 and can thus act as a selective receptor for STUbL targets. Indeed, we define key cooperative DNA repair functions for Cdc48-Ufd1-Npl4 and STUbL, thereby revealing a new signaling mechanism involving dual recruitment by SUMO and ubiquitin for Cdc48-Ufd1-Npl4 functions in maintaining genome stability."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m112.379768"xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Yates J.R."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Wohlschlegel J.A."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Vashisht A.A."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Aslanian A."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Nie M."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Boddy M.N."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Heideker J."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/author | "Prudden J."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/pages | "29610-29619"xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/title | "Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions."xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://purl.uniprot.org/core/volume | "287"xsd:string |
| http://purl.uniprot.org/citations/22730331 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22730331 |
| http://purl.uniprot.org/citations/22730331 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22730331 |
| http://purl.uniprot.org/uniprot/O42915#attribution-3C0C08B62703A90108D9D46BB8DB9289 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_O42915-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_O13351-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_P50524-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_P87176-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_Q9P3A7-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |
| http://purl.uniprot.org/uniprot/#_Q9USG9-mappedCitation-22730331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22730331 |