| http://purl.uniprot.org/citations/22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22750144 | http://www.w3.org/2000/01/rdf-schema#comment | "We studied interactive effects of insulinotropic GLP-1 and insulinostatic ghrelin on rat pancreatic islets. GLP-1 potentiated glucose-induced insulin release and cAMP production in isolated islets and [Ca(2+)](i) increases in single β-cells, and these potentiations were attenuated by ghrelin. Ghrelin suppressed [Ca(2+)](i) responses to an adenylate cyclase activator forskolin. Moreover, GLP-1-induced insulin release and cAMP production were markedly enhanced by [D-lys(3)]-GHRP-6, a ghrelin receptor antagonist, in isolated islets. These results indicate that both exogenous and endogenous islet-derived ghrelin counteracts glucose-dependent GLP-1 action to increase cAMP production, [Ca(2+)](i) and insulin release in islet β-cells, positioning ghrelin as a modulator of insulinotropic GLP-1."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.06.034"xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Yada T."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Sone H."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Damdindorj B."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Dezaki K."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Kakei M."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Kurashina T."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/author | "Rita R."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/pages | "2555-2562"xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/title | "Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet beta-cells."xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22750144 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22750144 |
| http://purl.uniprot.org/citations/22750144 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22750144 |
| http://purl.uniprot.org/uniprot/#_A6HLV7-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_A6IBT9-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_A6IBU0-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_A6JHT2-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_G3V6P5-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_Q5Y391-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_P01322-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |
| http://purl.uniprot.org/uniprot/#_P06883-mappedCitation-22750144 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22750144 |