DESCRIBE <http://purl.uniprot.org/citations/22759724>

Subject	Predicate	Object
http://purl.uniprot.org/citations/22759724	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22759724	http://www.w3.org/2000/01/rdf-schema#comment	" Background/aims A disturbed sleep-wake rhythm cycle can be seen in delirium and as melatonin regulates this cycle via melatonin receptors, genetic variations in these receptors may contribute to susceptibility to delirium. The purpose of this study was to investigate whether genetic variants in the melatonin receptor 1B (MTNR1B) gene are associated with delirium. Methods Elderly medical and hip surgery patients were included in the study. Five single-nucleotide polymorphisms (SNPs) were determined in the MTNR1B gene, i.e. rs18030962, rs3781638, rs10830963, rs156244 and rs4753426. Results In total, 53% of 171 hip fracture patients and 33% of 699 medical patients were diagnosed with delirium. None of the polymorphisms were found to be associated with the occurrence of delirium. Conclusion Future research could focus on sequencing this gene to look for other functional SNPs in relation to delirium."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.org/dc/terms/identifier	"doi:10.1159/000339231"xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/author	"Sijbrands E.J."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/author	"Tanck M.W."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/author	"van Munster B.C."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/author	"de Jonghe A."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/author	"de Rooij S."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/date	"2012"xsd:gYear
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/name	"Dement Geriatr Cogn Disord"xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/pages	"306-310"xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/title	"Polymorphisms in the melatonin receptor 1B gene and the risk of delirium."xsd:string
http://purl.uniprot.org/citations/22759724	http://purl.uniprot.org/core/volume	"33"xsd:string
http://purl.uniprot.org/citations/22759724	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/22759724
http://purl.uniprot.org/citations/22759724	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/22759724
http://purl.uniprot.org/uniprot/#_Q7Z583-mappedCitation-22759724	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/22759724
http://purl.uniprot.org/uniprot/#_P49286-mappedCitation-22759724	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/22759724
http://purl.uniprot.org/uniprot/#_Q8TEV7-mappedCitation-22759724	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/22759724
http://purl.uniprot.org/uniprot/Q8TEV7	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/22759724
http://purl.uniprot.org/uniprot/P49286	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/22759724
http://purl.uniprot.org/uniprot/Q7Z583	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/22759724