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http://purl.uniprot.org/citations/22801782http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22801782http://www.w3.org/2000/01/rdf-schema#comment"During mitotic spindle assembly, Aurora B kinase is part of an error correction mechanism that detaches microtubules from kinetochores that are under low mechanical tension. During anaphase, however, kinetochore-microtubule attachments must be maintained despite a drop of tension after removal of sister chromatid cohesion. Consistent with this requirement, Aurora B relocates away from chromosomes to the central spindle at the metaphase-anaphase transition. By ribonucleic acid interference screening using a phosphorylation biosensor, we identified two PP1-targeting subunits, Sds22 and Repo-Man, which counteracted Aurora B-dependent phosphorylation of the outer kinetochore component Dsn1 during anaphase. Sds22 or Repo-Man depletion induced transient pauses during poleward chromosome movement and a high incidence of chromosome missegregation. Thus, our study identifies PP1-targeting subunits that regulate the microtubule-kinetochore interface during anaphase for faithful chromosome segregation."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.org/dc/terms/identifier"doi:10.1083/jcb.201112112"xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Hyman A.A."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Held M."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Poser I."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Gerlich D.W."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Lampson M.A."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/author"Wurzenberger C."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/name"J Cell Biol"xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/pages"173-183"xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/title"Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores."xsd:string
http://purl.uniprot.org/citations/22801782http://purl.uniprot.org/core/volume"198"xsd:string
http://purl.uniprot.org/citations/22801782http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22801782
http://purl.uniprot.org/citations/22801782http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22801782
http://purl.uniprot.org/uniprot/Q14B71#attribution-6CA9E605D777CB1B13EF37BE74678D2Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/Q69YH5#attribution-6A49A9CB7931354F19F9FEAA4DF7573Ehttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/Q69YH5#attribution-6CA9E605D777CB1B13EF37BE74678D2Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/Q15435#attribution-6A49A9CB7931354F19F9FEAA4DF7573Ehttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/Q15435#attribution-6CA9E605D777CB1B13EF37BE74678D2Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/P36873#attribution-6A49A9CB7931354F19F9FEAA4DF7573Ehttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/Q3UM45#attribution-6CA9E605D777CB1B13EF37BE74678D2Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/#_A0A087WRA7-mappedCitation-22801782http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22801782
http://purl.uniprot.org/uniprot/#_D3Z5P7-mappedCitation-22801782http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22801782