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http://purl.uniprot.org/citations/22818666http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22818666http://www.w3.org/2000/01/rdf-schema#comment"Homozygosity for a 32 bp deletion in CCR5 (CCR5-Δ32/Δ32) is associated with strong resistance against HIV-1 infection. Several HLA types have been associated to improved viral control and/or delayed progression to AIDS. We report a unique HIV-1 infected individual homozygous for CCR5-Δ32/Δ32 and carrier of HLA-A*2402 and HLA-B*5701. In comparison with earlier data and although a replication competent virus has been isolated, the patient presents better immune status, response to treatment and disease evolution, which may be related to the control exerted by HLA class I restricted T cell immunity. Importantly, the accumulation of protective factors does not warrant a complete protection to HIV infection and the subsequent life-long treatment."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.org/dc/terms/identifier"doi:10.1016/j.imbio.2012.06.012"xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Martinez M.A."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Bach V."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Este J.A."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Ballana E."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Brander C."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Pou C."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Clotet B."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Paredes R."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Riveira-Munoz E."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Santos J.R."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Parera M."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Badia R."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Casadella M."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/author"Noguera M."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/name"Immunobiology"xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/pages"543-547"xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/title"HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Delta32/Delta32."xsd:string
http://purl.uniprot.org/citations/22818666http://purl.uniprot.org/core/volume"218"xsd:string
http://purl.uniprot.org/citations/22818666http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22818666
http://purl.uniprot.org/citations/22818666http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22818666
http://purl.uniprot.org/uniprot/#_A0A0A7C543-mappedCitation-22818666http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22818666