| http://purl.uniprot.org/citations/22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22850116 | http://www.w3.org/2000/01/rdf-schema#comment | "DNA fragmentation is the hallmark of apoptotic cells and mainly mediated by the DNA fragmentation factor DFF40(CAD)/DFF45(ICAD). DFF40 is a novel nuclease, whereas DFF45 is an inhibitor that can suppress the nuclease activity. Apoptotic DNA fragmentation in the fly is controlled by four DFF-related proteins, known as Drep1, 2, 3 and 4. However, the functions of Drep2 and Drep3 are totally unknown. Here, we found that Drep2 is a novel nuclease whose activity is inhibited by Drep3 through a tight interaction with the CIDE domain. Our results suggest that the fly has dual apoptotic DNA fragmentation systems: Drep1: Drep4 and Drep2: Drep3 complexes."xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.07.056"xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/author | "Park O.K."xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/author | "Park H.H."xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/pages | "3085-3089"xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/title | "Dual apoptotic DNA fragmentation system in the fly: Drep2 is a novel nuclease of which activity is inhibited by Drep3."xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22850116 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22850116 |
| http://purl.uniprot.org/citations/22850116 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22850116 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFF6-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFQ3-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_A8DY77-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q7K304-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_O61464-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q0E9B7-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q6NR36-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q95S67-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q9V3H0-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q9U786-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q9U787-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q8T4H5-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |
| http://purl.uniprot.org/uniprot/#_Q9NDR2-mappedCitation-22850116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22850116 |