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http://purl.uniprot.org/citations/22891633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22891633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22891633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/22891633http://www.w3.org/2000/01/rdf-schema#comment"Campylobacter and Helicobacter species express a 6-amino-6-deoxyfutalosine N-ribosylhydrolase (HpMTAN) proposed to function in menaquinone synthesis. BuT-DADMe-ImmA is a 36 pM transition state analogue of HpMTAN, and the crystal structure of the enzyme-inhibitor complex reveals the mechanism of inhibition. BuT-DADMe-ImmA has a MIC(90) value of <8 ng/mL for Helicobacter pylori growth but does not cause growth arrest in other common clinical pathogens, thus demonstrating potential as an H. pylori-specific antibiotic."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.org/dc/terms/identifier"doi:10.1021/bi3009664"xsd:string
http://purl.uniprot.org/citations/22891633http://purl.org/dc/terms/identifier"doi:10.1021/bi3009664"xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Almo S.C."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Almo S.C."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Evans G.B."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Evans G.B."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Wang S."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Wang S."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Schramm V.L."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Schramm V.L."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Tyler P.C."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Tyler P.C."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Norris G.E."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Norris G.E."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Brown R.L."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Brown R.L."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Du Q."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Du Q."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Haapalainen A.M."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Haapalainen A.M."xsd:string
http://purl.uniprot.org/citations/22891633http://purl.uniprot.org/core/author"Rinaldo-Matthis A."xsd:string