| http://purl.uniprot.org/citations/22901814 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22901814 | http://www.w3.org/2000/01/rdf-schema#comment | "Understanding the in vivo dynamics of protein localization and their physical interactions is important for many problems in biology. To enable systematic protein function interrogation in a multicellular context, we built a genome-scale transgenic platform for in vivo expression of fluorescent- and affinity-tagged proteins in Caenorhabditis elegans under endogenous cis regulatory control. The platform combines computer-assisted transgene design, massively parallel DNA engineering, and next-generation sequencing to generate a resource of 14,637 genomic DNA transgenes, which covers 73% of the proteome. The multipurpose tag used allows any protein of interest to be localized in vivo or affinity purified using standard tag-based assays. We illustrate the utility of the resource by systematic chromatin immunopurification and automated 4D imaging, which produced detailed DNA binding and cell/tissue distribution maps for key transcription factor proteins."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2012.08.001"xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Kim S.K."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Hyman A.A."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Xu X."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Snyder M."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Waterston R.H."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Zinke A."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Stewart A.F."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Niu W."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Preston E."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Sarov M."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Schloissnig S."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Pozniakovski A."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Reinke V."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Hasse S."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Murray J.I."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Ejsmont R.K."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Janette J."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Reis K."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Angermann K."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Enst S."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Janosch S."xsd:string |
| http://purl.uniprot.org/citations/22901814 | http://purl.uniprot.org/core/author | "Rupprecht M."xsd:string |