http://purl.uniprot.org/citations/22922005 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22922005 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22922005 | http://www.w3.org/2000/01/rdf-schema#comment | "ARHGAP21 is a 217 kDa RhoGAP protein shown to modulate cell migration through the control of Cdc42 and FAK activities. In the present work a 250 kDa-ARHGAP21 was identified by mass spectrometry. This modified form is differentially expressed among cell lines and human primary cells. Co-immunoprecipitations and in vitro SUMOylation confirmed ARHGAP21 specific modification by SUMO2/3 and mapped the SUMOylation site to ARHGAP21 lysine K1443. Immunofluorescence staining revealed that ARHGAP21 co-localizes with SUMO2/3 in the cytoplasm and membrane compartments. Interestingly, our results suggest that ARHGAP21 SUMOylation may be related to cell proliferation. Therefore, SUMOylation of ARHGAP21 may represent a way of guiding its function."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.08.012"xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.08.012"xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Traina F."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Traina F."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Novello J.C."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Novello J.C."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Martins-de-Souza D."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Martins-de-Souza D."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Archangelo L.F."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Archangelo L.F."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Bigarella C.L."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Bigarella C.L."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Barcellos K.S."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Barcellos K.S."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Olalla Saad S.T."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Olalla Saad S.T."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Vieira Ferro K.P."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/author | "Vieira Ferro K.P."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/22922005 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |