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http://purl.uniprot.org/citations/22948913http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22948913http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22948913http://www.w3.org/2000/01/rdf-schema#comment"The crystal structure of the protein augmenter of liver regeneration containing a 14-residue hexahistidine purification tag (hsALR) has been determined to 2.4 Å resolution by Cd-SAD using a highly redundant data set collected on a rotating-anode home X-ray source and processed in 1998. The hsALR crystal structure is a tetramer composed of two homodimers bridged by a novel Cd(2)Cl(4)O(6) cluster via binding to the side-chain carboxylate groups of two solvent-exposed aspartic acid residues. A comparison with the native sALR tetramer shows that the cluster dramatically changes the hsALR dimer-dimer interface, which can now better accommodate the extra 14 N-terminal residues associated with the purification tag. The refined 2.4 Å resolution structure is in good agreement with both the X-ray data (R(cryst) of 0.165, R(free) of 0.211) and the expected stereochemistry (r.m.s. deviations from ideality for bond lengths and bond angles of 0.007 Å and 1.15°, respectively)."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.org/dc/terms/identifier"doi:10.1107/s0907444912022561"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.org/dc/terms/identifier"doi:10.1107/s0907444912022561"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Habel J."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Habel J."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Rose J.P."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Rose J.P."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Wang B.C."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Wang B.C."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Florence Q."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Florence Q."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Swindell J.T. II"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Swindell J.T. II"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Wu C.K."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/author"Wu C.K."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/name"Acta Crystallogr. D"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/name"Acta Crystallogr. D"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/pages"1128-1133"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/pages"1128-1133"xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/title"The structure of augmenter of liver regeneration crystallized in the presence of 50 mM CdCl2 reveals a novel Cd2Cl4O6 cluster that aids in crystal packing."xsd:string
http://purl.uniprot.org/citations/22948913http://purl.uniprot.org/core/title"The structure of augmenter of liver regeneration crystallized in the presence of 50 mM CdCl2 reveals a novel Cd2Cl4O6 cluster that aids in crystal packing."xsd:string