| http://purl.uniprot.org/citations/22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22968996 | http://www.w3.org/2000/01/rdf-schema#comment | "The effects of the amino acid copolymers used in the therapy of experimental autoimmune encephalomyelitis, poly(Y,E,A,K)(n) (Copaxone(®)) and poly(Y,F,A,K)(n), on murine myeloid cells have been investigated. After administration of these copolymers to mice, increases in several splenic myeloid cell populations were observed, including CD11b(+) CD11c(+) dendritic cells. The latter were the major splenic cell type that secreted CCL22 (macrophage-derived chemokine) on stimulation with amino acid copolymers. CCL22 secretion was also stimulated from bone marrow-derived dendritic cells (BMDC) generated with GM-CSF in much larger amounts than from bone marrow-derived macrophages generated with M-CSF. Moreover, CCL22 secretion could also be obtained using BMDC generated from two different types of MHC II(-/-) mice, indicating that an innate immune receptor is involved. Finally, incubation of these BMDC or splenic dendritic cells with naive CD4(+) CD25(-) T cells resulted in formation of CD4(+) CD25(HI) Foxp3 T cells (~25% of which were Foxp3(+)). The number of these regulatory cells was doubled by pretreatment of BMDC with amino acid copolymers."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.org/dc/terms/identifier | "doi:10.1093/intimm/dxs087"xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/author | "Kawamoto N."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/author | "Strominger J.L."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/author | "Kondo N."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/author | "Ohnishi H."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/name | "Int Immunol"xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/pages | "53-65"xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/title | "The role of dendritic cells in the generation of CD4(+) CD25(HI) Foxp3(+) T cells induced by amino acid copolymers."xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/22968996 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22968996 |
| http://purl.uniprot.org/citations/22968996 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22968996 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B3-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_Q0PM15-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_Q0PM16-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_A0A1S5WLE4-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_A0A494B9G5-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_A0A494B9U2-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_A0A1S5WLF0-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_P06342-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_P06343-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_P06345-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |
| http://purl.uniprot.org/uniprot/#_P06346-mappedCitation-22968996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22968996 |