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http://purl.uniprot.org/citations/22975311http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22975311http://www.w3.org/2000/01/rdf-schema#comment"The motility, angiogenesis and metastasis-stimulating factor Autotaxin (Atx), over expressed by human neuroblastomas (NB), is constitutively expressed by human Nmyc-amplified SK-N-BE and non-Nmyc-amplified SH-SY5Y NB cells. Here, we characterise a novel Atx transcriptional mechanism, utilised by both cell lines, that is restricted to the first 285bp of the Atx promoter and involves AP-1 and SP transcription factors, acting through a CRE/AP-1-like element at position -142 to -149 and a GAbox at position -227 to -235 relative to the Atx translational start site. This novel transcriptional mechanism can be inhibited by internally initiated SP-3 and the natural phenol curcumin."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2012.08.026"xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Stracke M.L."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Sano K."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Gulino A."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Cappabianca L."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Farina A.R."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Mackay A.R."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Horowitz J.M."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Ruggeri P."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Di Ianni N."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Merolle S."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/author"Ragone M."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/pages"3681-3691"xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/title"Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin."xsd:string
http://purl.uniprot.org/citations/22975311http://purl.uniprot.org/core/volume"586"xsd:string
http://purl.uniprot.org/citations/22975311http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22975311
http://purl.uniprot.org/citations/22975311http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22975311
http://purl.uniprot.org/uniprot/#_A0A166VE84-mappedCitation-22975311http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22975311
http://purl.uniprot.org/uniprot/#_A0A1W2PPD9-mappedCitation-22975311http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22975311
http://purl.uniprot.org/uniprot/#_B4DRZ1-mappedCitation-22975311http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22975311
http://purl.uniprot.org/uniprot/#_B4DJD3-mappedCitation-22975311http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22975311