| http://purl.uniprot.org/citations/22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22994707 | http://www.w3.org/2000/01/rdf-schema#comment | "The diffuse large B-cell lymphoma (DLBCL) encompasses two major groups of tumors with uneven survival outcomes--germinal center B-cell (GCB) and non-germinal center B-cell (non-GCB). In the present study, we investigated the expression of GCB markers (BCL-6 and CD10) and non-GCB markers (CD138 and MUM-1) in an effort to evaluate their prognostic value. Paraffin-embedded tumor biopsies of 46 Jordanian DLBCL patients were analyzed, retrospectively, by immunohistochemistry to investigate the expression of BCL-6, CD10, CD138 and MUM-1. In addition, survival curves were calculated with reference to marker expression, age, sex and nodal involvement. Positive expression of BCL-6, CD10, CD138 and MUM-1 was shown in 78%, 61%, 39% and 91% of the cases, respectively, that of BCL-6 being associated with better overall survival (p = 0.02), whereas positive CD138 was linked with poor overall survival (p = 0.01). The expression of CD10 and MUM-1 had no impact on the overall survival. Among the clinical characteristics studied, diagnosis at an early age, nodal involvement and maleness were associated with a higher overall survival for DLBCL patients. Our results underline the importance of BCL-6 as a marker of better prognosis and CD138 as a marker of poor prognosis for DLBCL patients."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.org/dc/terms/identifier | "doi:10.7314/apjcp.2012.13.7.3037"xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/author | "Bodoor K."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/author | "Haddad Y."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/author | "Matalka I."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/author | "Gharaibeh W."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/author | "Hayajneh R."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/name | "Asian Pac J Cancer Prev"xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/pages | "3037-3046"xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/title | "Evaluation of BCL-6, CD10, CD138 and MUM-1 expression in diffuse large B-cell lymphoma patients: CD138 is a marker of poor prognosis."xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/22994707 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22994707 |
| http://purl.uniprot.org/citations/22994707 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22994707 |
| http://purl.uniprot.org/uniprot/#_B4DRQ9-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_B7ZKY6-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_P08473-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_P18827-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
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| http://purl.uniprot.org/uniprot/#_L7Z660-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_L7ZC27-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_L8E8E1-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/#_Q3KQS6-mappedCitation-22994707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22994707 |
| http://purl.uniprot.org/uniprot/P18827 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22994707 |