| http://purl.uniprot.org/citations/23027702 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23027702 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytokinesis in eukaryotes involves specific arrays of microtubules (MTs), which are known as the central spindle in animals, the anaphase spindle in yeasts, and the phragmoplast in plants. In plants, a mitogen-activated protein kinase (MAPK) cascade stimulates the turnover of phragmoplast MTs, which allows the expansion of the phragmoplast that is essential for cytokinesis including the formation of cell plates. A prerequisite for activation of this cascade is the interaction between mitotic kinesin NACK1 in tobacco (HINKEL in Arabidopsis) and MAPK kinase kinase NPK1 (ANP1, 2, 3 in Arabidopsis). Other members of this cascade are NQK1 MAPK kinase and NRK1/NTF6 MAPK in tobacco and the respective orthologs in Arabidopsis. All the components in the pathway (designated the NACK-PQR pathway) concentrate at the midzone of the phragmoplast in plant cells during cytokinesis. Downstream MAPKs in both plant species phosphorylate microtubule-associated protein 65 (MAP65). Interestingly, activities of components in the NACK-PQR pathway are downregulated by depolymerization of MTs. In the present review, we summarize current views on the mechanisms involved in activating the kinase cascade, a role of MAP65 phosphorylation by MAPK during cytokinesis, and the feedback mechanism for regulating inactivation of the kinase cascade."xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.org/dc/terms/identifier | "doi:10.1002/cm.21072"xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/author | "Machida Y."xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/author | "Sasabe M."xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/name | "Cytoskeleton (Hoboken)"xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/pages | "913-918"xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/title | "Regulation of organization and function of microtubules by the mitogen-activated protein kinase cascade during plant cytokinesis."xsd:string |
| http://purl.uniprot.org/citations/23027702 | http://purl.uniprot.org/core/volume | "69"xsd:string |
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| http://purl.uniprot.org/uniprot/#_Q8S905-mappedCitation-23027702 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23027702 |
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| http://purl.uniprot.org/uniprot/Q8S905 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23027702 |
| http://purl.uniprot.org/uniprot/O22040 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23027702 |