| http://purl.uniprot.org/citations/23056243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23056243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23056243 | http://www.w3.org/2000/01/rdf-schema#comment | "In a genome-wide screen for alpha-helical coiled coil motifs aiming at structurally defined vaccine candidates we identified PFF0165c. This protein is exported in the trophozoite stage and was named accordingly Trophozoite exported protein 1 (Tex1). In an extensive preclinical evaluation of its coiled coil peptides Tex1 was identified as promising novel malaria vaccine candidate providing the rational for a comprehensive cell biological characterization of Tex1. Antibodies generated against an intrinsically unstructured N-terminal region of Tex1 and against a coiled coil domain were used to investigate cytological localization, solubility and expression profile. Co-localization experiments revealed that Tex1 is exported across the parasitophorous vacuole membrane and located to Maurer's clefts. Change in location is accompanied by a change in solubility: from a soluble state within the parasite to a membrane-associated state after export to Maurer's clefts. No classical export motifs such as PEXEL, signal sequence/anchor or transmembrane domain was identified for Tex1."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0046112"xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0046112"xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Frank G."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Frank G."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Corradin G."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Corradin G."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Felger I."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Felger I."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Kajava A.V."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Kajava A.V."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Beck H.P."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Beck H.P."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Mueller D."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Mueller D."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Dietz O."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Dietz O."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Kulangara C."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Kulangara C."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Luedin S."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Luedin S."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Moser M."xsd:string |
| http://purl.uniprot.org/citations/23056243 | http://purl.uniprot.org/core/author | "Moser M."xsd:string |