http://purl.uniprot.org/citations/23063642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23063642 | http://www.w3.org/2000/01/rdf-schema#comment | "Mammalian homologs of lin28: Lin28 and Lin28B block the post-transcriptional processing of the let-7 family of miRNAs. We report that in vitro the terminal stem-loop region of the let-7g miRNA precursor (pre-let-7g) required to bind Lin28B is restricted to 24 nucleotides (nt) including the 3' GGAG motif. Additionally, full length Lin28B is required for efficient binding to pre-let-7g and the stoichiometry of the complex is 1:1. Molecular dynamics (MD) simulations reveal the interactions of the pre-let-7g stem-loop and the GGAG motif in the stem region to the cold shock domain (CSD) and to the zinc knuckle domain (ZKD) of Lin28B, respectively."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.09.034"xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/author | "Brutschy B."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/author | "Hoffmann J."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/author | "Filipek S."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/author | "Ghoshdastider U."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/author | "Ali P.S."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/pages | "3986-3990"xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/title | "Recognition of the let-7g miRNA precursor by human Lin28B."xsd:string |
http://purl.uniprot.org/citations/23063642 | http://purl.uniprot.org/core/volume | "586"xsd:string |
http://purl.uniprot.org/citations/23063642 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23063642 |
http://purl.uniprot.org/citations/23063642 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23063642 |
http://purl.uniprot.org/uniprot/#_A7E2T3-mappedCitation-23063642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23063642 |
http://purl.uniprot.org/uniprot/#_Q6ZN17-mappedCitation-23063642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23063642 |
http://purl.uniprot.org/uniprot/Q6ZN17 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23063642 |
http://purl.uniprot.org/uniprot/A7E2T3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23063642 |