http://purl.uniprot.org/citations/23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23064758 | http://www.w3.org/2000/01/rdf-schema#comment | "Spasmolytic polypeptide/trefoil family factor 2 expressing metaplasia (SPEM) is induced by oxyntic atrophy and is known as a precancerous or paracancerous lesion. We now have sought to determine whether hepatocyte growth factor (HGF) influences the development of SPEM and oxyntic atrophy. DMP-777, a parietal cell ablating reagent, was administered to HGF activator (HGFA)-deficient mice and wild-type mice. Gastric mucosal lineage changes were analyzed in the DMP-777 treatment phase and recovery phase. Both wild-type and HGFA knockout mice showed SPEM, and there was no difference in SPEM development. However, after cessation of DMP-777, HGFA-deficient mice showed delayed recovery from SPEM compared with wild-type mice. Foveolar cell hyperplasia and the increase in proliferating cells after parietal cell loss were reduced in HGFA-deficient mice. The HGFA does not affect emergence of SPEM. However, the absence of HGFA signaling causes a delay in the recovery from SPEM to normal glandular composition. HGFA also promotes foveolar cell hyperplasia and mucosal cell proliferation in acute oxyntic injury."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajpgi.00107.2012"xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Fukushima T."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Kataoka H."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Nomura S."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Yamagata Y."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Esumi H."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Kaminishi M."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Goldenring J.R."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Seto Y."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/author | "Aikou S."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/name | "Am J Physiol Gastrointest Liver Physiol"xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/pages | "G1254-61"xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/title | "Loss of HGF activator inhibits foveolar hyperplasia induced by oxyntic atrophy without altering gastrin levels."xsd:string |
http://purl.uniprot.org/citations/23064758 | http://purl.uniprot.org/core/volume | "303"xsd:string |
http://purl.uniprot.org/citations/23064758 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23064758 |
http://purl.uniprot.org/citations/23064758 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23064758 |
http://purl.uniprot.org/uniprot/#_A0A0J9YUU2-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |
http://purl.uniprot.org/uniprot/#_A0A0J9YUY6-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |
http://purl.uniprot.org/uniprot/#_A8C1W3-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |
http://purl.uniprot.org/uniprot/#_Q9R098-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |
http://purl.uniprot.org/uniprot/#_Q3TDU8-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |
http://purl.uniprot.org/uniprot/#_Q545J3-mappedCitation-23064758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23064758 |