| http://purl.uniprot.org/citations/23070364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23070364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23070364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/23070364 | http://www.w3.org/2000/01/rdf-schema#comment | "ChaC1 is a mammalian proapoptic protein of unknown function induced during endoplasmic reticulum stress. We show using in vivo studies and novel in vitro assays that the ChaC family of proteins function as γ-glutamyl cyclotransferases acting specifically to degrade glutathione but not other γ-glutamyl peptides. The overexpression of these proteins (but not the catalytically dead E>Q mutants) led to glutathione depletion and enhanced apoptosis in yeast. The ChaC family is conversed across all phyla and represents a new pathway for glutathione degradation in living cells, and the first cytosolic pathway for glutathione degradation in mammalian cells."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2012.156"xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2012.156"xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Kumar A."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Kumar A."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Kaur A."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Kaur A."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Bachhawat A.K."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Bachhawat A.K."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Sengupta S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Sengupta S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Maity S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Maity S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Sengupta S.'"xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Sengupta S.'"xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Tikoo S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/author | "Tikoo S."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/23070364 | http://purl.uniprot.org/core/pages | "1095-1101"xsd:string |