http://purl.uniprot.org/citations/23079727 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23079727 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23079727 | http://www.w3.org/2000/01/rdf-schema#comment | "In mammals, transcriptional autorepression by Period (PER) and Cryptochrome (CRY) protein complexes is essential for the generation of circadian rhythms. We have identified CAVIN-3 as a new, cytoplasmic PER2-interacting protein influencing circadian clock properties. Thus, CAVIN-3 loss- and gain-of-function shortened and lengthened, respectively, the circadian period in fibroblasts and affected PER:CRY protein abundance and interaction. While depletion of protein kinase Cδ (PKCδ), a known partner of CAVIN-3, had little effect on circadian gene expression, CAVIN-3 required the PKCδ-binding site to exert its effect on period length. This suggests the involvement of yet uncharacterized protein kinases. Finally, CAVIN-3 activity in circadian gene expression was independent of caveolae."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2012.158"xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2012.158"xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Schneider K."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Schneider K."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Kurzchalia T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Kurzchalia T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Gatfield D."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Gatfield D."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Schibler U."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Schibler U."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Andersin T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Andersin T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Kocher T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/author | "Kocher T."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/pages | "1138-1144"xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/pages | "1138-1144"xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/title | "CAVIN-3 regulates circadian period length and PER:CRY protein abundance and interactions."xsd:string |
http://purl.uniprot.org/citations/23079727 | http://purl.uniprot.org/core/title | "CAVIN-3 regulates circadian period length and PER:CRY protein abundance and interactions."xsd:string |