http://purl.uniprot.org/citations/23085393 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23085393 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23085393 | http://www.w3.org/2000/01/rdf-schema#comment | "We identified urate oxidase (UOX) as a target of SIRT5 by comparing mitochondrial proteins in livers of SIRT5-overexpressing transgenic (SIRT5 Tg) and wild-type mice by using two-dimensional electrophoresis. Acetylation levels of UOX in liver of SIRT5 Tg mice were approximately half of those in wild-type mice, and UOX activity was significantly increased. Invitro-synthesized UOX protein was acetylated when incubated with mitochondria from wild-type mice liver but the levels were less when incubated with those from SIRT5 Tg mice liver. These results suggest that SIRT5 activates UOX through deacetylation in mouse liver mitochondria."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.10.009"xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.10.009"xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Ogura K."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Ogura K."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Ogura M."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Ogura M."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Inagaki N."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Inagaki N."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Tanaka D."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/author | "Tanaka D."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/pages | "4076-4081"xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/pages | "4076-4081"xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/title | "SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/title | "SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice."xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/volume | "586"xsd:string |
http://purl.uniprot.org/citations/23085393 | http://purl.uniprot.org/core/volume | "586"xsd:string |