| http://purl.uniprot.org/citations/23085713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23085713 | http://www.w3.org/2000/01/rdf-schema#comment | "Although it has been clearly established that well-positioned histone H2A.Z-containing nucleosomes flank the nucleosome-depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information is transmitted through the cell cycle is unknown. We show here that in mouse trophoblast stem cells, the amount of histone H2A.Z at promoters decreased during S phase, coinciding with homotypic (H2A.Z-H2A.Z) nucleosomes flanking the TSS becoming heterotypic (H2A.Z-H2A). To our surprise these nucleosomes remained heterotypic at M phase. At the TSS, we identified an unstable heterotypic histone H2A.Z-containing nucleosome in G1 phase that was lost after DNA replication. These dynamic changes at the TSS mirror a global expansion of the NDR at S and M phases, which, unexpectedly, is unrelated to transcriptional activity. Coincident with the loss of histone H2A.Z at promoters, histone H2A.Z is targeted to the centromere when mitosis begins."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.2424"xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Williams R."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Parker B.J."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Huttley G.A."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Nekrasov M."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Tremethick D.J."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Jack C."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Soboleva T.A."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/author | "Amrichova J."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/name | "Nat Struct Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/pages | "1076-1083"xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/title | "Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics."xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://purl.uniprot.org/core/volume | "19"xsd:string |
| http://purl.uniprot.org/citations/23085713 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23085713 |
| http://purl.uniprot.org/citations/23085713 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23085713 |
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| http://purl.uniprot.org/uniprot/#_Q3TFU6-mappedCitation-23085713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23085713 |
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| http://purl.uniprot.org/uniprot/Q3UA95 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23085713 |