http://purl.uniprot.org/citations/23096252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23096252 | http://www.w3.org/2000/01/rdf-schema#comment | "PurposeTo investigate whether rs11190870 near LBX1 correlates with the susceptibility or curve progression of adolescent idiopathic scoliosis (AIS) in a Han Chinese population.MethodsA total of 949 AIS patients and 976 age-matched healthy controls were recruited. All the subjects were genotyped using the PCR-based invader assay. Case-control study and case-only study were performed to define the contribution of rs11190870 to predisposition and curve severity of AIS. Additionally, we further conducted a meta-analysis of the study findings together with those of previously reported studies.ResultsA significant association of rs11190870 with AIS was observed in the Han Chinese population (P = 1.8 × 10(-9); odd ratio = 1.51; 95 % confidence interval = 1.33-1.71), and AIS patients with TT genotype had a larger Cobb angle than those with TC or CC genotype (P = 0.005). The meta-analysis confirmed that the positive association of this SNP with AIS in the East Asian population.ConclusionsThe SNP rs11190870 near LBX1 is associated with both susceptibility and curve progression of AIS."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00586-012-2532-4"xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Jiang H."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Qiu Y."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Zhu Z."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Yan H."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Qiu X."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Dai J."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/author | "Qian B."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/name | "Eur Spine J"xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/pages | "282-286"xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/title | "Association of rs11190870 near LBX1 with adolescent idiopathic scoliosis susceptibility in a Han Chinese population."xsd:string |
http://purl.uniprot.org/citations/23096252 | http://purl.uniprot.org/core/volume | "22"xsd:string |
http://purl.uniprot.org/citations/23096252 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23096252 |
http://purl.uniprot.org/citations/23096252 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23096252 |
http://purl.uniprot.org/uniprot/#_P52954-mappedCitation-23096252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23096252 |
http://purl.uniprot.org/uniprot/#_O60863-mappedCitation-23096252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23096252 |
http://purl.uniprot.org/uniprot/#_Q6LBH2-mappedCitation-23096252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23096252 |
http://purl.uniprot.org/uniprot/P52954 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23096252 |
http://purl.uniprot.org/uniprot/O60863 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23096252 |
http://purl.uniprot.org/uniprot/Q6LBH2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23096252 |