http://purl.uniprot.org/citations/23105107 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23105107 | http://www.w3.org/2000/01/rdf-schema#comment | "The AAA-ATPase Vps4 is critical for function of the multivesicular body sorting pathway, which impacts cellular phenomena ranging from receptor down-regulation to viral budding to cytokinesis. Vps4 activity is stimulated by the interaction between Vta1 and Vps60, but the structural basis for this interaction is unclear. The fragment Vps60(128-186) was reported to display the full activity of Vps60. Vta1 interacts with Vps60 using its N-terminal domain (Vta1NTD). In this work, the structure of Vps60(128-186) in complex with Vta1NTD was determined using NMR techniques, demonstrating a novel recognition mode of the microtubule-interacting and transport (MIT) domain in which Vps60(128-186) interacts with Vta1NTD through helices α4' and α5', extending over Vta1NTD MIT2 domain helices 1-3. The Vps60 binding does not result in Vta1 conformational changes, further revealing the fact that Vps4 ATPase is enhanced by the interaction between Vta1 and Vps60 in an unanticipated manner."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m112.390724"xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Cao C."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Gong F."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Ju J."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Liu J."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Liu M."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Shen J."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Zhao B."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Yang Z."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Xu Z."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Lan W."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/author | "Vild C."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/pages | "43899-43908"xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/title | "Structural basis of molecular recognition between ESCRT-III-like protein Vps60 and AAA-ATPase regulator Vta1 in the multivesicular body pathway."xsd:string |
http://purl.uniprot.org/citations/23105107 | http://purl.uniprot.org/core/volume | "287"xsd:string |
http://purl.uniprot.org/citations/23105107 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23105107 |
http://purl.uniprot.org/citations/23105107 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23105107 |
http://purl.uniprot.org/uniprot/#_A0A8H4BX99-mappedCitation-23105107 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23105107 |
http://purl.uniprot.org/uniprot/#_A0A6A5Q4G9-mappedCitation-23105107 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23105107 |
http://purl.uniprot.org/uniprot/#_Q06263-mappedCitation-23105107 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23105107 |