| http://purl.uniprot.org/citations/23109900 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23109900 | http://www.w3.org/2000/01/rdf-schema#comment | "Little is known about the interactions of single nucleotide polymorphisms (SNPs) and overweight/obesity on blood pressure levels. The present study was undertaken to detect 10 lipid-related gene SNPs and their interactions with overweight/obesity on blood pressure levels. Genotyping of ATP-binding cassette transporter A1 (ABCA-1) V825I, acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) rs1044925, low density lipoprotein receptor (LDL-R) AvaII hepatic lipase gene (LIPC) -250G > A, endothelial lipase gene (LIPG) 584C > T, methylenetetrahydrofolate reductase (MTHFR) 677C > T, the E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP) rs3757354, proprotein convertase subtilisin-like kexin type 9 (PCSK9) E670G, peroxisome proliferator-activated receptor delta (PPARD) +294T > C, and Scavenger receptor class B type 1 (SCARB1) rs5888 was performed in 978 normal weight and 751 overweight/obese subjects. The interactions were detected by factorial regression analysis. The genotypes of ACAT-1 AC, LIPC GA and AA, and SCARB1 TT; LDL-R A-A- and LIPC GA; and SCARB1 TT were interacted with overweight/obesity to increase systolic, diastolic blood pressure (SBP, DBP) and pulse pressure (PP) levels; respectively. The genotypes of ACAT-1 CC; ACAT-1 AA and CC were interacted with overweight/obesity to decrease SBP, PP levels (p < 0.01-0.001); respectively. The differences in blood pressure levels between normal weight and overweight/obese subjects might partly result from different interactions of several SNPs and overweight/obesity."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.org/dc/terms/identifier | "doi:10.3390/ijms130912062"xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Li M."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Cao X.L."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Miao L."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Wu D.F."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Liu W.Y."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Aung L.H.H."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Yan T.T."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Yin R.X."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/author | "Long X.J."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/name | "Int J Mol Sci"xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/pages | "12062-12081"xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/title | "Several lipid-related gene polymorphisms interact with overweight/obesity to modulate blood pressure levels."xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/23109900 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23109900 |
| http://purl.uniprot.org/citations/23109900 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23109900 |
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| http://purl.uniprot.org/uniprot/#_P11150-mappedCitation-23109900 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23109900 |
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| http://purl.uniprot.org/uniprot/#_A0A482KFZ6-mappedCitation-23109900 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23109900 |