http://purl.uniprot.org/citations/23121659 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23121659 | http://www.w3.org/2000/01/rdf-schema#comment | "Dendritic targeting of mRNAs encoding the microtubule-associated protein 2 (MAP2) in neurons involves a cis-acting dendritic targeting element. Two rat brain proteins, MAP2-RNA trans-acting protein (MARTA)1 and MARTA2, bind to the cis-element with both high affinity and specificity. In this study, affinity-purified MARTA2 was identified as orthologue of human far-upstream element binding protein 3. In neurons, it resides in somatodendritic granules and dendritic spines and associates with MAP2 mRNAs. Expression of a dominant-negative variant of MARTA2 disrupts dendritic targeting of endogenous MAP2 mRNAs, while not noticeably altering the level and subcellular distribution of polyadenylated mRNAs as a whole. Finally, MAP2 transcripts associate with the microtubule-based motor KIF5 and inhibition of KIF5, but not cytoplasmic dynein function disrupts extrasomatic trafficking of MAP2 mRNA granules. Thus, in neurons MARTA2 appears to represent a key trans-acting factor involved in KIF5-mediated dendritic targeting of MAP2 mRNAs."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.org/dc/terms/identifier | "doi:10.1111/jnc.12079"xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Kremmer E."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Richter D."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Schweizer M."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Buck F."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Kreienkamp H.J."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Kindler S."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Schob C."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Falley K."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Schepis A."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Rehbein M."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Zivraj K.H."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/author | "Olschlager-Schutt J."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/name | "J Neurochem"xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/pages | "670-684"xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/title | "The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons."xsd:string |
http://purl.uniprot.org/citations/23121659 | http://purl.uniprot.org/core/volume | "124"xsd:string |
http://purl.uniprot.org/citations/23121659 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23121659 |
http://purl.uniprot.org/citations/23121659 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23121659 |
http://purl.uniprot.org/uniprot/P56536#attribution-543BDDF1A6F1AC6B9974E52753F30850 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23121659 |
http://purl.uniprot.org/uniprot/A0A8I6ACQ5#attribution-543BDDF1A6F1AC6B9974E52753F30850 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23121659 |
http://purl.uniprot.org/uniprot/A0A8I6ACQ5#attribution-FA0387C5D93F17403DE11E332115C6B1 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23121659 |