| http://purl.uniprot.org/citations/23142580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23142580 | http://www.w3.org/2000/01/rdf-schema#comment | "CCN2 plays a critical role in the development of mesenchymal tissues such as cartilage and bone, and the binding of CCN2 to various cytokines and receptors regulates their signaling.By screening a protein array, we found that CCN2 could bind to fibroblast growth factor receptors (FGFRs) 2 and 3, with a higher affinity toward FGFR2.We ascertained that FGFR2 bound to CCN2 and that the binding of FGFR2 to FGF2 and FGF4 was enhanced by CCN2.CCN2 and FGF2 had a collaborative effect on the phosphorylation of ERK and the differentiation of osteoblastic cells.The present results indicate the biological significance of the binding of CCN2 to FGFR2 in bone metabolism."xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.10.038"xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/author | "Kubota S."xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/author | "Takigawa M."xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/author | "Aoyama E."xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/pages | "4270-4275"xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/title | "CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling."xsd:string |
| http://purl.uniprot.org/citations/23142580 | http://purl.uniprot.org/core/volume | "586"xsd:string |
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