| http://purl.uniprot.org/citations/23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23148892 | http://www.w3.org/2000/01/rdf-schema#comment | "Environmental constraints challenge cell homeostasis and thus require a tight regulation of metabolic activity. We have previously reported that the γ-aminobutyric acid (GABA) metabolism is crucial for Arabidopsis salt tolerance as revealed by the NaCl hypersensitivity of the GABA transaminase (GABA-T, At3g22200) gaba-t/pop2-1 mutant. In this study, we demonstrate that GABA-T deficiency during salt stress causes root and hypocotyl developmental defects and alterations of cell wall composition. A comparative genome-wide transcriptional analysis revealed that expression levels of genes involved in carbon metabolism, particularly sucrose and starch catabolism, were found to increase upon the loss of GABA-T function under salt stress conditions. Consistent with the altered mutant cell wall composition, a number of cell wall-related genes were also found differentially expressed. A targeted quantitative analysis of primary metabolites revealed that glutamate (GABA precursor) accumulated while succinate (the final product of GABA metabolism) significantly decreased in mutant roots after 1 d of NaCl treatment. Furthermore, sugar concentration was twofold reduced in gaba-t/pop2-1 mutant roots compared with wild type. Together, our results provide strong evidence that GABA metabolism is a major route for succinate production in roots and identify GABA as a major player of central carbon adjustment during salt stress."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.org/dc/terms/identifier | "doi:10.1111/pce.12033"xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Berger A."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Mouille G."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Soubigou-Taconnat L."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Bouchereau A."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "El Amrani A."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Renault H."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/author | "Deleu C."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/name | "Plant Cell Environ"xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/pages | "1009-1018"xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/title | "gamma-Aminobutyric acid transaminase deficiency impairs central carbon metabolism and leads to cell wall defects during salt stress in Arabidopsis roots."xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/23148892 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23148892 |
| http://purl.uniprot.org/citations/23148892 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23148892 |
| http://purl.uniprot.org/uniprot/Q94CE5#attribution-C60ED3948F8A1276F47797075D15F16E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_A0A178V944-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_A0A178VL84-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_F4K007-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_F4K6Z4-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_F4K6Z5-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_F4K6Z6-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |
| http://purl.uniprot.org/uniprot/#_A0A2H1ZEI5-mappedCitation-23148892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23148892 |