| http://purl.uniprot.org/citations/23174504 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23174504 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23174504 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23174504 | http://www.w3.org/2000/01/rdf-schema#comment | "Recent outbreaks in monkeys have proven that canine distemper virus (CDV) causes diseases in a wide range of mammals. CDV uses SLAM and nectin4 as receptors to replicate in susceptible animals. Here, we show that human nectin4, but not human SLAM, is fully functional as a CDV receptor. The CDV Ac96I strain hardly replicated in nectin4-expressing human epithelial NCI-H358 cells, but readily adapted to grow in them. Unsurprisingly, no amino acid change in the H protein was required for the adaptation. The original Ac96I strain possessed a truncated C protein, and a subpopulation possessing the intact C protein was selected after growth in NCI-H358 cells. Other CDV strains possessing the intact C protein showed significantly higher growth abilities in NCI-H358 cells than the Ac96I strain with the truncated C protein. These findings suggest that the C protein is functional in human epithelial cells and critical for CDV replication in them."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.virol.2012.10.033"xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.virol.2012.10.033"xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.virol.2012.10.033"xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Chen S."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Chen S."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Chen S."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Kuroda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Kuroda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Kuroda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Sakai K."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Sakai K."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Sakai K."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Takeda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Takeda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Takeda M."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Yamaguchi R."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Yamaguchi R."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Yamaguchi R."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Maenaka K."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Maenaka K."xsd:string |
| http://purl.uniprot.org/citations/23174504 | http://purl.uniprot.org/core/author | "Maenaka K."xsd:string |