| http://purl.uniprot.org/citations/2325643 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2325643 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2325643 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated the gene for a novel growth regulator, amphiregulin (AR), that is evolutionarily related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). AR is a bifunctional growth modulator: it interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. The 84-amino-acid mature protein is embedded within a 252-amino-acid transmembrane precursor, an organization similar to that of the TGF-alpha precursor. Human placenta and ovaries were found to express significant amounts of the 1.4-kilobase AR transcript, implicating AR in the regulation of normal cell growth. In addition, the AR gene was localized to chromosomal region 4q13-4q21, a common breakpoint for acute lymphoblastic leukemia."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.10.5.1969-1981.1990"xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.10.5.1969-1981.1990"xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Green J.M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Green J.M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Todaro G.J."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Todaro G.J."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Shoyab M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Shoyab M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Neubauer M.G."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Neubauer M.G."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Disteche C.M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Disteche C.M."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "McDonald V.L."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "McDonald V.L."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Plowman G.D."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/author | "Plowman G.D."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/pages | "1969-1981"xsd:string |
| http://purl.uniprot.org/citations/2325643 | http://purl.uniprot.org/core/pages | "1969-1981"xsd:string |