http://purl.uniprot.org/citations/23261508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23261508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23261508 | http://www.w3.org/2000/01/rdf-schema#comment | "Antimicrobial peptides (AMPs) play important roles in innate immunity. One such AMP, epinecidin-1, exhibits antibacterial effects in zebrafish. In the current study, we aimed to identify the antimicrobial-associated proteins affected by epinecidin-1 treatment, and to unravel the underlying antimicrobial molecular mechanisms of epinecidin-1. We analyzed proteome changes in epinecidin-1-treated zebrafish using two-dimensional electrophoresis (2DE) coupled to mass spectrometry. Several differentially expressed proteins were identified, some of which were validated by real-time quantitative RT-PCR. The differentially expressed proteins were mapped onto Ingenuity Pathway Analysis canonical pathways, to construct a possible protein-protein interacting network regulated by epinecidin-1; this network suggested a potential role of epinecindin-1 in cytoskeletal assembly and organization. Our findings imply that epinecidin-1 may stabilize the cytoskeleton network in host cells, thereby promoting resistance to bacterial infection."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.fsi.2012.11.032"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/author | "Chen J.Y."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/author | "Chen J.Y."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/author | "Huang T.C."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/author | "Huang T.C."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/name | "Fish Shellfish Immunol."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/name | "Fish Shellfish Immunol"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/pages | "593-598"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/pages | "593-598"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/title | "Proteomic and functional analysis of zebrafish after administration of antimicrobial peptide epinecidin-1."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/title | "Proteomic and functional analysis of zebrafish after administration of antimicrobial peptide epinecidin-1."xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/volume | "34"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://purl.uniprot.org/core/volume | "34"xsd:string |
http://purl.uniprot.org/citations/23261508 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23261508 |
http://purl.uniprot.org/citations/23261508 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23261508 |
http://purl.uniprot.org/citations/23261508 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23261508 |
http://purl.uniprot.org/citations/23261508 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23261508 |
http://purl.uniprot.org/uniprot/G8JL17 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/23261508 |
http://purl.uniprot.org/uniprot/#_G8JL17-citation-23261508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23261508 |
http://purl.uniprot.org/uniprot/#_A3KPP4-mappedCitation-23261508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23261508 |