| http://purl.uniprot.org/citations/23271731 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23271731 | http://www.w3.org/2000/01/rdf-schema#comment | "The signal transducer and activator of transcription 3 (STAT3), a nuclear transcription factor, is also present in mitochondria and regulates cellular respiration in a transcriptional-independent manner. The mechanism of STAT3 import into mitochondria remains obscure. In this report we show that mitochondrial-localized STAT3 resides in the inner mitochondrial membrane. In vitro import studies show that the gene associated with retinoid interferon induced cell mortality 19 (GRIM-19), a complex I subunit that acts as a chaperone to recruit STAT3 into mitochondria. In addition, GRIM-19 enhances the integration of STAT3 into complex I. A S727A mutation in STAT3 reduces its import and assembly even in the presence of GRIM-19. Together, our studies unveil a novel chaperone function for GRIM-19 in the recruitment of STAT3 into mitochondria."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m112.378984"xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Mohammed F."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Sepuri N.B."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Larner A.C."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Anjaneyulu M."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Anugula C."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/author | "Tammineni P."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/pages | "4723-4732"xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/title | "The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain."xsd:string |
| http://purl.uniprot.org/citations/23271731 | http://purl.uniprot.org/core/volume | "288"xsd:string |
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