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http://purl.uniprot.org/citations/23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23297414http://www.w3.org/2000/01/rdf-schema#comment"Dynamin mediates various membrane fission events, including the scission of clathrin-coated vesicles. Here, we provide direct evidence for cooperative membrane recruitment of dynamin with the BIN/amphiphysin/Rvs (BAR) proteins, endophilin and amphiphysin. Surprisingly, endophilin and amphiphysin recruitment to membranes was also dependent on binding to dynamin due to auto-inhibition of BAR-membrane interactions. Consistent with reciprocal recruitment in vitro, dynamin recruitment to the plasma membrane in cells was strongly reduced by concomitant depletion of endophilin and amphiphysin, and conversely, depletion of dynamin dramatically reduced the recruitment of endophilin. In addition, amphiphysin depletion was observed to severely inhibit clathrin-mediated endocytosis. Furthermore, GTP-dependent membrane scission by dynamin was dramatically elevated by BAR domain proteins. Thus, BAR domain proteins and dynamin act in synergy in membrane recruitment and GTP-dependent vesicle scission."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m112.444869"xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"Meinecke M."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"McMahon H.T."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"Hon W.C."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"Mittal R."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"Boucrot E."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/author"Camdere G."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/name"J Biol Chem"xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/pages"6651-6661"xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/title"Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission."xsd:string
http://purl.uniprot.org/citations/23297414http://purl.uniprot.org/core/volume"288"xsd:string
http://purl.uniprot.org/citations/23297414http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23297414
http://purl.uniprot.org/citations/23297414http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23297414
http://purl.uniprot.org/uniprot/#_P63010-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_P63027-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_Q14247-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_Q15642-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_O15144-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_O15145-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_P01130-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_P01133-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414
http://purl.uniprot.org/uniprot/#_P01135-mappedCitation-23297414http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23297414