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| http://purl.uniprot.org/citations/23299028 | http://www.w3.org/2000/01/rdf-schema#comment | "L-selectin is a type I transmembrane cell adhesion molecule that is expressed on the surface of most circulating leukocytes. Studies in L-selectin knockout mice reveal a prominent role for this glycoprotein in health and disease, regulating leucocyte recruitment to peripheral lymph nodes (e.g. naïve T-cells) and sites of acute and chronic inflammation (e.g. monocytes and neutrophils). Clinical trials have revealed L-selectin as a promising target in some acute and chronic inflammatory diseases. Unearthing the intracellular signals that act directly downstream of L-selectin may also expose novel therapeutic targets in a cell type/disease-specific manner. This review will focus on L-selectin-dependent signalling - exploring the different signals that potentially arise from distinct phases of the multi-step adhesion cascade and the contribution of known binding partners of L-selectin in this response."xsd:string |
| http://purl.uniprot.org/citations/23299028 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.biocel.2012.12.023"xsd:string |
| http://purl.uniprot.org/citations/23299028 | http://purl.uniprot.org/core/author | "Ivetic A."xsd:string |
| http://purl.uniprot.org/citations/23299028 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23299028 | http://purl.uniprot.org/core/name | "Int J Biochem Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/23299028 | http://purl.uniprot.org/core/pages | "550-555"xsd:string |
| http://purl.uniprot.org/citations/23299028 | http://purl.uniprot.org/core/title | "Signals regulating L-selectin-dependent leucocyte adhesion and transmigration."xsd:string |
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