| http://purl.uniprot.org/citations/2332496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2332496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2332496 | http://www.w3.org/2000/01/rdf-schema#comment | "Ro/SS-A antibodies are found in a number of human autoimmune disorders including Sjogren's syndrome and several systemic lupus erythematosus-related disorders. These heterogeneous autoantibodies are known to recognize several distinct cellular antigens. With synthetic oligonucleotides corresponding to amino acid sequence information we have isolated a full-length cDNA clone which encodes a human Ro ribonucleoprotein autoantigen. The 1,890-base pair clone contains an open reading frame that encodes a 417-amino acid, 48-kD polypeptide that migrates aberrantly at 60 kD by SDS-PAGE. Rabbit antibodies raised against this protein's recently described amino-terminal epitope react with a previously identified 52-kD human Ro protein and immunoprecipitate the human cytoplasmic RNAs. Ultraviolet light cross-linking studies suggest that this Ro protein binds each of the four major human cytoplasmic RNAs. The deduced amino acid sequence is 63% homologous to an Onchocerca volvulus antigen. Southern filter hybridization analysis indicates that this gene is not highly polymorphic and exists as a single copy in the human genome. Chromosomal localization studies place this gene on the short arm of chromosome 19 near the gene encoding the low density lipoprotein receptor."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.org/dc/terms/identifier | "doi:10.1172/jci114582"xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.org/dc/terms/identifier | "doi:10.1172/jci114582"xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Siciliano M.J."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Siciliano M.J."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Hanke J."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Hanke J."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Itoh Y."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Itoh Y."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Bachinski L.L."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Bachinski L.L."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Capra J.D."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Capra J.D."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Lieu T.S."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Lieu T.S."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Lux F.A."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Lux F.A."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "McCauliffe D.P."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "McCauliffe D.P."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Newkirk M.M."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Newkirk M.M."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Reichlin M."xsd:string |
| http://purl.uniprot.org/citations/2332496 | http://purl.uniprot.org/core/author | "Reichlin M."xsd:string |