| http://purl.uniprot.org/citations/23362208 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23362208 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23362208 | http://www.w3.org/2000/01/rdf-schema#comment | "The differentiation of hair (H) and non-hair (N) cells in the Arabidopsis thaliana root epidermis is dependent on positional relationships with underlying cortical cells. We previously found that histone acetylation relays positional information and that a mutant altered in the histone deacetylase gene family member HISTONE DEACETYLASE 18 (HDA18) exhibits altered H and N epidermal cell patterning. Here, we report that HDA18 has in vitro histone deacetylase activity and that both mutation and overexpression of HDA18 led to cells at the N position having H fate. The HDA18 protein physically interacted with histones related to a specific group of kinase genes, which are demonstrated in this study to be components of a positional information relay system. Both down- and upregulation of HDA18 increased transcription of the targeted kinase genes. Interestingly, the acetylation levels of histone 3 lysine 9 (H3K9), histone 3 lysine 14 (H3K14) and histone 3 lysine 18 (H3K18) at the kinase genes were differentially affected by down- or upregulation of HDA18, which explains why the transcription levels of the four HDA18-target kinase genes increased in all lines with altered HDA18 expression. Our results reveal the surprisingly complex mechanism by which HDA18 affects cellular patterning in Arabidopsis root epidermis."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.112.107045"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.112.107045"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Chen X."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Chen X."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Liu C."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Liu C."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Xu Z.H."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Xu Z.H."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Li L.C."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Li L.C."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Bai S.N."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Bai S.N."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Chen W.Q."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/author | "Chen W.Q."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/pages | "257-269"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/pages | "257-269"xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/title | "HDA18 affects cell fate in Arabidopsis root epidermis via histone acetylation at four kinase genes."xsd:string |
| http://purl.uniprot.org/citations/23362208 | http://purl.uniprot.org/core/title | "HDA18 affects cell fate in Arabidopsis root epidermis via histone acetylation at four kinase genes."xsd:string |