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http://purl.uniprot.org/citations/23391777http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23391777http://www.w3.org/2000/01/rdf-schema#comment"The significance of carbonic anhydrase (CA-IX) expression in endocervical glandular lesions was determined to assess the utility of CA-IX immunohistochemistry for the identification of gastric-type endocervical adenocarcinoma and its related lesions. In this study, lobular endocervical glandular hyperplasia (LEGH) (n=5), atypical LEGH (ALEGH) (n=6), and endocervical adenocarcinomas, including usual-type (UEA) (n=6) and gastric-type (GAS) (n=7), were examined by immunohistochemistry for CA-IX expression. The proportion of positive staining and intensity was evaluated as between 0 and 3+. All 13 UEAs and GASs were positive for CA-IX, with 9 cases showing 3+ staining, and 8 cases showing positive areas exceeding 50%. All 11 LEGHs were positive for CA-IX, with all cases showing 50% or more positive areas, although only one case was 3+ positive. Five of 6 ALEGHs were positive for CA-IX, with 4 cases showing 3+ positivity in 100% of the lesion. Non-neoplastic glands were negative for CA-IX, although reserve cell populations and tubal metaplasias were positive for CA-IX. Although CA-IX appears to be involved in tumor progression and may be diagnostically useful in cases of endocervical adenocarcinoma and its precursors, LEGH can be a pitfall, and staining results should be combined with morphology."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.org/dc/terms/identifier"doi:10.1016/j.prp.2012.12.003"xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Mikami Y."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Haga H."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Konishi I."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Nagura M."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Teramoto N."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/author"Minamiguchi S."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/name"Pathol Res Pract"xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/pages"173-178"xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/title"Carbonic anhydrase type IX expression in lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix."xsd:string
http://purl.uniprot.org/citations/23391777http://purl.uniprot.org/core/volume"209"xsd:string
http://purl.uniprot.org/citations/23391777http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23391777
http://purl.uniprot.org/citations/23391777http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23391777
http://purl.uniprot.org/uniprot/#_A0A0S2Z341-mappedCitation-23391777http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/#_A0A0S2Z3D0-mappedCitation-23391777http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/#_A1ECK7-mappedCitation-23391777http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/#_Q16790-mappedCitation-23391777http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/Q16790http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/A0A0S2Z341http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/A0A0S2Z3D0http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23391777
http://purl.uniprot.org/uniprot/A1ECK7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/23391777