RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/23414806http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23414806http://www.w3.org/2000/01/rdf-schema#comment"A novel series of 3-O-carbamoyl erythromycin A derived analogs, labeled carbamolides, with activity versus resistant bacterial isolates of staphylococci (including macrolide and oxazolidinone resistant strains) and streptococci are reported. An (R)-2-aryl substituent on a pyrrolidine carbamate appeared to be critical for achieving potency against resistant strains. Crystal structures showed a distinct aromatic interaction between the (R)-2-aryl (3-pyridyl for 4d) substituent on the pyrrolidine and G2484 (G2505, Escherichia coli) of the Deinococcus radiodurans 50S ribosome (3.2Å resolution)."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2013.01.067"xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Han S."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Nguyen T.T."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Subashi T.A."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Maguire B.A."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Chen J.M."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Huband M.D."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Marr E.S."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Shanmugasundaram V."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"McCurdy S.P."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Granskog K."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/author"Magee T.V."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/name"Bioorg Med Chem Lett"xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/pages"1727-1731"xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/title"Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates."xsd:string
http://purl.uniprot.org/citations/23414806http://purl.uniprot.org/core/volume"23"xsd:string
http://purl.uniprot.org/citations/23414806http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23414806
http://purl.uniprot.org/citations/23414806http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23414806
http://purl.uniprot.org/uniprot/#_P49228-mappedCitation-23414806http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23414806
http://purl.uniprot.org/uniprot/#_Q9RRG8-mappedCitation-23414806http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23414806
http://purl.uniprot.org/uniprot/#_Q9RSH2-mappedCitation-23414806http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23414806
http://purl.uniprot.org/uniprot/#_Q9RSJ5-mappedCitation-23414806http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23414806