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http://purl.uniprot.org/citations/23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23417122http://www.w3.org/2000/01/rdf-schema#comment"The linkage of adherens junctions to the actin cytoskeleton is essential for cell adhesion. The contribution of the cadherin-catenin complex to the interaction between actin and the adherens junction remains an intensely investigated subject that centres on the function of α-catenin, which binds to cadherin through β-catenin and can bind F-actin directly or indirectly. Here, we delineate regions within Drosophila α-Catenin (α-Cat) that are important for adherens junction performance in static epithelia and dynamic morphogenetic processes. Moreover, we address whether persistent α-catenin-mediated physical linkage between cadherin and F-actin is crucial for cell adhesion and characterize the functions of α-catenin monomers and dimers at adherens junctions. Our data support the view that monomeric α-catenin acts as an essential physical linker between the cadherin-β-catenin complex and the actin cytoskeleton, whereas α-catenin dimers are cytoplasmic and form an equilibrium with monomeric junctional α-catenin."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.org/dc/terms/identifier"doi:10.1038/ncb2685"xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Ikura M."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Ishiyama N."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Desai R."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Sarpal R."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Tepass U."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/author"Pellikka M."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/name"Nat Cell Biol"xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/pages"261-273"xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/title"Monomeric alpha-catenin links cadherin to the actin cytoskeleton."xsd:string
http://purl.uniprot.org/citations/23417122http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/23417122http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/23417122
http://purl.uniprot.org/citations/23417122http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/23417122
http://purl.uniprot.org/uniprot/P26231#attribution-1970B61242440CE22AB2BF1968132E95http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/P35220#attribution-1970B61242440CE22AB2BF1968132E95http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/P35220#attribution-3F643C27B4635CB0F6D212880A585E9Chttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/Q61301#attribution-1970B61242440CE22AB2BF1968132E95http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/#_A0A0N4SUZ7-mappedCitation-23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/#_A0A494BA24-mappedCitation-23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/#_A0A494BAD0-mappedCitation-23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/#_A0A494BAM5-mappedCitation-23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23417122
http://purl.uniprot.org/uniprot/#_A0A494BBA4-mappedCitation-23417122http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/23417122