http://purl.uniprot.org/citations/23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23417122 | http://www.w3.org/2000/01/rdf-schema#comment | "The linkage of adherens junctions to the actin cytoskeleton is essential for cell adhesion. The contribution of the cadherin-catenin complex to the interaction between actin and the adherens junction remains an intensely investigated subject that centres on the function of α-catenin, which binds to cadherin through β-catenin and can bind F-actin directly or indirectly. Here, we delineate regions within Drosophila α-Catenin (α-Cat) that are important for adherens junction performance in static epithelia and dynamic morphogenetic processes. Moreover, we address whether persistent α-catenin-mediated physical linkage between cadherin and F-actin is crucial for cell adhesion and characterize the functions of α-catenin monomers and dimers at adherens junctions. Our data support the view that monomeric α-catenin acts as an essential physical linker between the cadherin-β-catenin complex and the actin cytoskeleton, whereas α-catenin dimers are cytoplasmic and form an equilibrium with monomeric junctional α-catenin."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb2685"xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Ikura M."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Ishiyama N."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Desai R."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Sarpal R."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Tepass U."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/author | "Pellikka M."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/name | "Nat Cell Biol"xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/pages | "261-273"xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/title | "Monomeric alpha-catenin links cadherin to the actin cytoskeleton."xsd:string |
http://purl.uniprot.org/citations/23417122 | http://purl.uniprot.org/core/volume | "15"xsd:string |
http://purl.uniprot.org/citations/23417122 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23417122 |
http://purl.uniprot.org/citations/23417122 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23417122 |
http://purl.uniprot.org/uniprot/P26231#attribution-1970B61242440CE22AB2BF1968132E95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/P35220#attribution-1970B61242440CE22AB2BF1968132E95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/P35220#attribution-3F643C27B4635CB0F6D212880A585E9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/Q61301#attribution-1970B61242440CE22AB2BF1968132E95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/#_A0A0N4SUZ7-mappedCitation-23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/#_A0A494BA24-mappedCitation-23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/#_A0A494BAD0-mappedCitation-23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/#_A0A494BAM5-mappedCitation-23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23417122 |
http://purl.uniprot.org/uniprot/#_A0A494BBA4-mappedCitation-23417122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23417122 |