http://purl.uniprot.org/citations/23434585 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23434585 | http://www.w3.org/2000/01/rdf-schema#comment | "The STAT3 transcription factor plays a central role in a wide range of cancer types where it is over-expressed. Previously, phosphorylation of this protein was thought to be a prerequisite for direct binding to DNA. However, we have now shown complete binding of a purified unphosphorylated STAT3 (uSTAT3) core directly to M67 DNA, the high affinity STAT3 target DNA sequence, by a protein electrophoretic mobility shift assay (PEMSA). Binding to M67 DNA was inhibited by addition of increasing concentrations of a phosphotyrosyl peptide. X-ray crystallography demonstrates one mode of binding that is similar to that known for the STAT3 core phosphorylated at Y705."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.01.065"xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Shah R."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Wilderspin A.F."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Bui T.T."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Drake A.F."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Palmer J."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Parkinson G.N."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Neidle S."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Zinzalla G."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Rahman K.M."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Thurston D.E."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Collie G.W."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Husby J."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/author | "Nkansah E."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/pages | "833-839"xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/title | "Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography."xsd:string |
http://purl.uniprot.org/citations/23434585 | http://purl.uniprot.org/core/volume | "587"xsd:string |
http://purl.uniprot.org/citations/23434585 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23434585 |
http://purl.uniprot.org/citations/23434585 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23434585 |
http://purl.uniprot.org/uniprot/P42227#attribution-0611A7674C4A239D7595B0203C4C4C31 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23434585 |
http://purl.uniprot.org/uniprot/#_A0A7I2V395-mappedCitation-23434585 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23434585 |