| http://purl.uniprot.org/citations/23454641 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23454641 | http://www.w3.org/2000/01/rdf-schema#comment | "The native HIV-1 Env complex consists of a gp120/gp41 trimer, but surface plasmon resonance (SPR)-directed binding studies for gp120-binding agents were almost exclusively performed on monomeric gp120. SPR-directed binding kinetics of monomeric gp120 and trimeric gp140 were investigated for a broad variety of envelope (Env)-binding agents. Similar kinetics for carbohydrate-binding agents (CBAs), the antibody 2G12 and sCD4 were observed, irrespective of the oligomeric state of gp120 that either contain the native mixture of complex and high-mannose N-glycans or that contain exclusively oligomannose N-glycans. The generally comparable kinetic properties of CBA, 2G12 and sCD4 binding to monomeric gp120 and trimeric gp140 indicate that monomeric gp120 is a good surrogate molecule for native HIV-1 Env trimer to investigate the binding affinities of Env-binding compounds."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.02.037"xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Igarashi Y."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Tanaka H."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Balzarini J."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Xue J."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Van Damme E.J."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Sanders R.W."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "Hoorelbeke B."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "LiWang P.J."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/author | "van Montfort T."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/pages | "860-866"xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/title | "HIV-1 envelope trimer has similar binding characteristics for carbohydrate-binding agents as monomeric gp120."xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://purl.uniprot.org/core/volume | "587"xsd:string |
| http://purl.uniprot.org/citations/23454641 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23454641 |
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| http://purl.uniprot.org/uniprot/#_P04578-mappedCitation-23454641 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23454641 |
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| http://purl.uniprot.org/uniprot/P11218 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23454641 |