| http://purl.uniprot.org/citations/23470432 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23470432 | http://www.w3.org/2000/01/rdf-schema#comment | "Heme oxygenase-1 (HO-1) is an inducible rate-limiting enzyme for heme degradation. Here, we studied the HO-1 expression in an open-skull weight-drop-induced traumatic brain injury, with a focus on the early phase, most amenable to therapy. In normal rat brains of our study, HO-1 cells were rarely observed. Significant parenchymal accumulation of HO-1 non-neuron cells was observed 18 h post-traumatic brain injury and increased continuously during the investigating time. We also observed that the accumulated HO-1 non-neuron cells were mainly distributed in the perilesional areas and showed activated microglia/macrophage phenotypes with ramified or amoeboid morphologic characteristics. Further double-labeling experiments showed that most HO-1 non-neuron cells coexpressed CD68 and CD163, but not glial fibrillary acid protein. Our data suggest that HO-1 expression defines a subtype of activated microglia/macrophages involved in the early processes following traumatic brain injury."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.org/dc/terms/identifier | "doi:10.1097/wnr.0b013e32835f2810"xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/author | "Luo B."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/author | "Zhang Z.'"xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/author | "Schluesener H.J."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/name | "Neuroreport"xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/pages | "281-286"xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/title | "Lesional accumulation of heme oxygenase-1+ microglia/macrophages in rat traumatic brain injury."xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://purl.uniprot.org/core/volume | "24"xsd:string |
| http://purl.uniprot.org/citations/23470432 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23470432 |
| http://purl.uniprot.org/citations/23470432 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23470432 |
| http://purl.uniprot.org/uniprot/#_A0A8L2UJE9-mappedCitation-23470432 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23470432 |
| http://purl.uniprot.org/uniprot/#_P06762-mappedCitation-23470432 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23470432 |
| http://purl.uniprot.org/uniprot/A0A8L2UJE9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23470432 |
| http://purl.uniprot.org/uniprot/P06762 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23470432 |