http://purl.uniprot.org/citations/23474800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23474800 | http://www.w3.org/2000/01/rdf-schema#comment | "PurposeThe most common long-term complication of joint arthroplasty is aseptic loosening. The proinflammatory cytokines secreted by macrophages are involved in aseptic loosening. Recently, a novel proinflammatory cytokine IL-17C was reported to participate in inflammatory diseases by synergising with proinflammatory cytokines. However, the relationship between IL-17C and the aseptic loosening is unclear.MethodsThe tissues around aseptic loosened implants were collected during revision surgery and handled by formalin fixation and embedded in paraffin. The presence of IL-17C in the tissues around the aseptic loosened implants was investigated in 12 aseptic loosening patients using immunofluorescence.ResultsThe presence of IL-17C protein in the tissues around aseptic loosened implants was detected by immunofluorescence. There are no statistical differences between optical density of IL-17C in aseptic loosening samples and in rheumatoid arthritis samples (positive control).ConclusionsThese results suggest the presence of IL-17C in aseptic loosening. Interleukin-17C was related to the inflammation of aseptic loosening, possibly by contributing to the inflammation and osteolysis in the tissues surrounding aseptic loosened implants."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00264-013-1812-x"xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Li Z."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Sheng P."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Yu S."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Xiao J."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Zhai Q."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Hou C."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/author | "Li Z.'"xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/name | "Int Orthop"xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/pages | "953-959"xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/title | "Presence of interleukin-17C in the tissue around aseptic loosened implants."xsd:string |
http://purl.uniprot.org/citations/23474800 | http://purl.uniprot.org/core/volume | "37"xsd:string |
http://purl.uniprot.org/citations/23474800 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23474800 |
http://purl.uniprot.org/citations/23474800 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23474800 |
http://purl.uniprot.org/uniprot/#_Q9P0M4-mappedCitation-23474800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23474800 |
http://purl.uniprot.org/uniprot/Q9P0M4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/23474800 |