| http://purl.uniprot.org/citations/23507704 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23507704 | http://www.w3.org/2000/01/rdf-schema#comment | "The aim of this study was to investigate the expression of glutamine metabolism-related proteins to determine whether glutamine is metabolized differently according to breast cancer molecular subtype. We generated a tissue microarray of 702 breast cancer patients and performed immunohistochemical staining for glutamine metabolism-related proteins, including glutaminase 1 (GLS1 (GLS)), glutamate dehydrogenase (GDH (H6PD)), and amino acid transporter-2 (ASCT2 (SLC1A5)), which were separately evaluated in tumor and stroma compartments and then analyzed by breast cancer molecular subtypes. Breast cancers were classified as follows: 293 luminal A (41.7%), 166 luminal B (23.6%), 67 HER2 type (9.6%), and 176 TNBC (25.1%). HER2 type showed the highest stromal GLS1 (P=0.001), tumoral GDH (P=0.001), stromal GDH (P<0.001), and tumoral ASCT (P<0.001) expression. We identified differential expression of glutamine metabolism-related proteins according to molecular subtype of breast cancer. The highest glutamine metabolic activity was seen in HER2-type breast cancer."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.org/dc/terms/identifier | "doi:10.1530/erc-12-0398"xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/author | "Kim D.H."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/author | "Jung W.H."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/author | "Koo J.S."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/name | "Endocr Relat Cancer"xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/pages | "339-348"xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/title | "Expression of glutamine metabolism-related proteins according to molecular subtype of breast cancer."xsd:string |
| http://purl.uniprot.org/citations/23507704 | http://purl.uniprot.org/core/volume | "20"xsd:string |
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