http://purl.uniprot.org/citations/23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23518915 | http://www.w3.org/2000/01/rdf-schema#comment | "Cervical cancer is a leading cause of cancer deaths in women worldwide and infection by high-risk human papillomavirus types is a precursor event. The cellular FLICE-like inhibitory protein (c-FLIP) has been found to be overexpressed in several types of cancers and could be associated with cervical cancer progression because of its ability to inhibit the apoptotic process. To detect c-FLIP expression in cervical cancer, an immunohistochemical staining was performed, using tissue microarrays, on a series of 536 archival biopsy samples, including normal cervical tissues, low-grade and high-grade squamous intraepithelial lesions, and squamous cervical carcinomas. The epithelium in the normal cervix and low-grade squamous intraepithelial lesions mainly stained negatively for c-FLIP, whereas high-grade intraepithelial lesions and cancer samples showed an elevated expression of c-FLIP. A direct association was observed between the increasing grade of the lesion and the intensity of c-FLIP staining, in which the frequency of intense c-FLIP expression increased from 12.5% in the normal tissue to 82.1% in the cervical cancer tissue. An increased expression of c-FLIP may be an important factor in the progression of cervical cancer. This finding could aid in identifying patients with preneoplastic lesions at greater risk of developing cervical cancer. c-FLIP expression in cervical tissue may be a potential cervical cancer progression marker."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.org/dc/terms/identifier | "doi:10.1097/pgp.0b013e31825d8064"xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Garcia P."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Tapia O."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Sidransky D."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Lopez J."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Sandoval A."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Leal P."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Roa J.C."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Brebi P."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Guerrero-Preston R."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/author | "Ili C.G."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/name | "Int J Gynecol Pathol"xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/pages | "316-322"xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/title | "Cellular FLICE-like inhibitory protein long form (c-FLIPL) overexpression is related to cervical cancer progression."xsd:string |
http://purl.uniprot.org/citations/23518915 | http://purl.uniprot.org/core/volume | "32"xsd:string |
http://purl.uniprot.org/citations/23518915 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23518915 |
http://purl.uniprot.org/citations/23518915 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23518915 |
http://purl.uniprot.org/uniprot/#_A0A024R3Y4-mappedCitation-23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23518915 |
http://purl.uniprot.org/uniprot/#_E9PAP3-mappedCitation-23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23518915 |
http://purl.uniprot.org/uniprot/#_A0A336TY74-mappedCitation-23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23518915 |
http://purl.uniprot.org/uniprot/#_B4DMB6-mappedCitation-23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23518915 |
http://purl.uniprot.org/uniprot/#_B4E361-mappedCitation-23518915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23518915 |