| http://purl.uniprot.org/citations/23535894 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23535894 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23535894 | http://www.w3.org/2000/01/rdf-schema#comment | "Import-Karyopherin or Importin proteins bind nuclear localization signals (NLSs) to mediate the import of proteins into the cell nucleus. Karyopherin β2 or Kapβ2, also known as Transportin, is a member of this transporter family responsible for the import of numerous RNA binding proteins. Kapβ2 recognizes a targeting signal termed the PY-NLS that lies within its cargos to target them through the nuclear pore complex. The recognition of PY-NLS by Kapβ2 is conserved throughout eukaryotes. Kap104, the Kapβ2 homolog in Saccharomyces cerevisiae, recognizes PY-NLSs in cargos Nab2, Hrp1, and Tfg2. We have determined the crystal structure of Kapβ2 bound to the PY-NLS of the mRNA processing protein Nab2 at 3.05-Å resolution. A seven-residue segment of the PY-NLS of Nab2 is observed to bind Kapβ2 in an extended conformation and occupies the same PY-NLS binding site observed in other Kapβ2·PY-NLS structures."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10969-013-9150-1"xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10969-013-9150-1"xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Almo S.C."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Almo S.C."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Bonanno J.B."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Bonanno J.B."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Hillerich B."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Hillerich B."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Love J.D."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Love J.D."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Chowdhury S."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Chowdhury S."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Glenn A.S."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Glenn A.S."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Hammonds J."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Hammonds J."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Seidel R.D."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Seidel R.D."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Toro R."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Toro R."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Sampathkumar P."xsd:string |
| http://purl.uniprot.org/citations/23535894 | http://purl.uniprot.org/core/author | "Sampathkumar P."xsd:string |