| http://purl.uniprot.org/citations/23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23550278 | http://www.w3.org/2000/01/rdf-schema#comment | "To analyze the expression profiles of N-a-acetyltransferase 10 protein (Naa10p/ARD1) and matrix metalloproteinase 9 (MMP-9) in human breast cancer and evaluate their possible prognostic values in breast cancer patients. Quantitative RT-PCR was used to evaluate mRNA expression of Naa10p and MMP-9 in 55 cases of fresh breast cancer tissues, and immunohistochemistry was performed for detecting Naa10p and MMP-9 proteins on breast cancer with tissue microarray containing 80 specimens. Furthermore, Naa10p and MMP-9 were measured in 253 breast cancer tissues from patients with up to 15-year follow-up. Survival curves were generated using the Kaplan-Meier method. Multivariate analysis was performed by using the Cox proportional hazard regression model to assess the prognostic values of Naa10p and MMP-9. Both Naa10p and MMP-9 expression in breast cancer tissues were significantly higher than those in the matched non-cancerous tissues (p = 0.000 for both). There was an inverse correlation between Naa10p and MMP-9 expression at mRNA and protein levels (p = 0.000 for both). Patients with MMP-9-positive expression had a poorer overall survival (OS) and disease-free survival (DFS) than those with MMP-9-negative expression (p = 0.001 for both). However, patients with Naa10p-positive expression had better OS and DFS (p = 0.000 for both). In addition, Naa10p-positive/MMP-9-negative patients had the best OS and DFS (p = 0.000 for both). In multivariate survival analysis, TNM stage, Naa10p expression, MMP-9 expression, and combined expression status of Naa10p/MMP-9 were independent prognostic factors related to OS (p = 0.000, 0.007, 0.012, and 0.000, respectively) and DFS (p = 0.000, 0.002, 0.014, and 0.000, respectively).The expression level of Naa10p was inversely correlated with that of MMP-9 in human breast cancer samples. Combined analysis of Naa10p and MMP-9 had a significantly increased value for determining the prognosis of breast cancer patients."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.org/dc/terms/identifier | "doi:10.1007/s12032-013-0562-3"xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Liu C."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Jiang B."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Dong B."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Qu L."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Wu J."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Xu Y."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Zeng Y."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Meng L."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/author | "Shou C."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/name | "Med Oncol"xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/pages | "562"xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/title | "Inverse correlation between Naa10p and MMP-9 expression and the combined prognostic value in breast cancer patients."xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/23550278 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23550278 |
| http://purl.uniprot.org/citations/23550278 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23550278 |
| http://purl.uniprot.org/uniprot/#_B4DFG1-mappedCitation-23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23550278 |
| http://purl.uniprot.org/uniprot/#_B7Z7V0-mappedCitation-23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23550278 |
| http://purl.uniprot.org/uniprot/#_B4DKJ7-mappedCitation-23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23550278 |
| http://purl.uniprot.org/uniprot/#_B7Z507-mappedCitation-23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23550278 |
| http://purl.uniprot.org/uniprot/#_B7Z747-mappedCitation-23550278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/23550278 |